Scientific Programme

The Young Crystallographers’ Group (YCG) Satellite Meeting Programme

The YCG satellite meeting is an opportunity for all early career researchers in the field of crystallography to present their work in a supportive and friendly environment, which will be run by fellow early career scientists.

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Monday 6 April, 2020
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13.00 - 13.30

YCG Plenary
Conference Auditorium 2
Chair: Natalie Tatum
Ehmke Pohl
(Durham University)
Virus-X – from bio-prospecting to new structures and functions

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13:30 – 16:00

YCG Research Talks
Conference Auditorium 2
Chairs: Natalie Tatum and Tom Roseveare
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13.30 - 13.45
Adam Crawshaw (Diamond Light Source Ltd)
Preparing protein micro-crystals for low background data collection at VMXm
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13.45 - 14.00
Anssi Peuronen (University of Sheffield)
Pitfalls in structure determination of M6Ln metallocages derived from sterically hindered ligands
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14.00 - 14.15
Alice Bumstead (University of Cambridge),
Investigating the Melting Behaviour of Polymorphic Zeolitic Imidazolate Frameworks
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14:15 – 14:45 Coffee Break
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14:45 – 16:00
YCG Research Talks
Conference Auditorium 2
Chairs: Tom Roseveare and Charlie McMonagle
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14.45 - 15.00
Lucy Hunter (Newcastle University)
Synthesis of stilbene based lanthanide metal-organic frameworks
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15.00 - 15.15
Lee Birchall (University of Kent)
Synthesis of novel co-crystals based on the spin-crossover complex [Fe(3-bpp)2]2+ using mechanochemistry
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15.15 - 15.30
MC Scicluna (University of Malta)
Covalent 1D Imine-Linked Ribbo
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15.30 - 15.45
Edward Broadhurst (University of Edinburgh)
Polymorph evolution during crystal growth studied by 3D electron diffraction
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15.45 - 16.00
RJ Young (University of Nottingham/University of Adelaide)
Photochemistry of Manganese Carbonyl Complexes in Metal-Organic Frameworks
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16:00 – 16:30 Break
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16:30 – 17:00
YCG Research Talks
Conference Auditorium 2
Chairs: Aly Abedeldaim and Tom Roseveare
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16.30 - 16.45
George Sackman (University of Oxford/Australian Nuclear Science and Technology Organisation)
A Tale of Two Crystals: Determining Hydrogen Positions Using Laue Neutron Diffraction
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16.45 - 17.00
FCN Firth (University of Cambridge)
Exploring the formation of Hf Metal-Organic Frameworks
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17.00 - 17.30
Parkin Lecture
Conference Auditorium 2
Chairs: Tom Roseveare and Charlie McMonagle
EH Driscoll (University of Birmingham)
The Building Blocks of Battery Technology: Inspiring the next generation of battery researchers
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17:30 – 18:30
YCG Annual General Meeting
Conference Auditorium 2
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18:30 – 19:00
Flash Presentations
Conference Auditorium 2
Chairs: Emma Wolpert and Anna Herlihy

19:00 – 21:00
Poster Session with dinner and wine
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Tuesday 7 April, 2020 

08:00 Registration opens for Main Meeting
[Registration open 08:00 – 18:00]

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08.45 - 09.15
YCG Plenary
Conference Auditorium 2
Chair: Natalie Johnson
Cheryl Doherty (GSK)
Exploring digital design for pharmaceutical solid forms

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09:15 – 11:10
YCG/IG Session
Conference Auditorium 2
Chairs: Natalie Johnson and Rachel Wilkinson
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Crystallography can lead to a wide range of exciting and varied careers. The start of this session will feature research talks exploring both academic and industrial research endeavours. This session will also offer a unique question and answer forum to discuss careers in crystallography via a selected panel of crystallographers who have taken different career paths. This session has been designed to provide greater information about the variety of careers available for young crystallographers, with attendees able to ask any and all questions they have about the careers to the panellists.

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09.15 - 09.30
Tom Smith (Newcastle University)
Automated imaging and image processing for high throughput small molecule crystallisations
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09.30 - 09.45
A Al-Ani (University of Bath)
Controlling Amorphization in solid state materials for enhanced pharmaceutical properties
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09:45 – 11:10
Careers Q and A
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11:10 – 11:30 Coffee Break

Main Meeting Programme
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Tuesday 7 April, 2020
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11.30 - 12.15
Lonsdale Lecture
Conference Auditorium 2

Chair: Aly Abedeldaim and Natalie Tatum
Lucy Clark (University of Liverpool)
Quantum Magnetism and Crystallographic Complexity in Mineral Materials
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12:15 – 13:00 Lunch Break and Exhibition
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12.15 – 12.45
PCG Annual General Meeting

Lecture Theatre RSLT07

13.00 - 14.10
Rosalind Franklin Centenary Lecture
Conference Auditorium 2

Chairs: TBC
Gabriel Waksman (UCL and Birkbeck)
Structural and Molecular Biology of large bacterial secretion machines
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14:20 – 15:50
PCG: Biominerals & Biomaterials
Lecture Theatre RSLT07
Chair: Julia Parker
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From the exquisite morphologies of coccoliths and the incredible hierarchical architecture of bone, to the engineering of implants and joint replacements, the structure of biominerals and biomaterials plays an integral role in determining their properties and function. This session will examine the importance of structure in both natural systems and biomedical devices, explore how their composition and assembly controls physical properties and look at how this can be exploited in the development of novel bioinspired materials.
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14.20 - 14.50
Keynote: Melinda Duer (University of Cambridge)
The Bare Bones of Biomineralization: new insights into bone mineral composition, structure and formation
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14:50 – 15:10
Yi-Yeoun Kim (University of Leeds)
Synthesis of Exceptional Single Crystal Nanocomposites challenges basic concepts in bio-inspired crystallisation
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15.10 - 15.30
Emily Arnold (Cranfield University)
XPDF Examination of Synthetic and Biogenic Biominerals
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15.30 - 15.50
Heera Singh (DAV University)
Crystallographic investigation of delafossite materials ABO2 for biomedical applications
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14:20 – 15:50
CCG: Advances in Software for Crystallography
Lecture Theatre RSLT06
Chair: Lucy Saunders
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This session aims to reveal the latest and exciting developments happening in crystallographic software. We encourage abstracts from those in the community working on software for chemical crystallography research. We want to know about the latest tools on offer. This could be in the areas of data processing, structure refinement, property calculation or structure investigation to name a few.
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14.20 - 14.50
Keynote: Mairi Haddow (Heriot-Watt University)
Can a solution for disordered molecules be automated?
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14.50 - 15.10
Ben Williams (Diamond Light Source)
Difficult data done quickly — dealing with the trickier cases of data reduction from single-crystal diffraction
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15.10 - 15.30
Ella Schmidt (University of Oxford)
Possibilities for RMC modelling for single crystal diffuse scattering in molecular materials
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15.30 - 15.50
Anuraha Pallipurath (University of Leeds/Rutherford Appleton Laboratory/University of Strathclyde)
Modelling the solution you crystallise from
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14:20 – 15:50
BSG: Structure-based drug design
Lecture Theatre RSLT05
Chair: Jane Endicott 
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Protein structures can assist drug development at all stages of the discovery pipeline, from choosing targets, through identifying hit matter, to supporting iterative medicinal chemistry to enhance potency, pharmacokinetics and pharmacodynamics.  Historically, structure-based drug design has addressed well characterised active sites by identifying potential molecular interactions to inform subsequent chemical synthesis.  Application of this approach has already contributed to the development of many potent and selective drugs. However, molecular targets with clear disease linkage can be extremely difficult to find, and for this reason more is being asked of structures in drug discovery campaigns. Examples of these new contributions include characterising and capturing biologically relevant protein conformations to help in the targeting of allosteric sites and identifying novel classes of target that depend on protein-protein and protein-DNA/RNA/lipid interactions. The keynote lecture will review key advances in the field over the last decade and future possible directions while reflecting on what a drug discovery campaign looks like from the structural biologist’s point of view.
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14.20 - 14.50
Keynote: TBC
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14.50 - 15.10
Rachel Skyner (Diamond Light Source)
Fragalysis: enabling fast, cheap, and effective progression of weak fragment hits to potent binders for novice users
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15.10 - 15.30
Sabrina Mackinnon (University of Oxford)
Crystallography-based fragment screening to develop novel, allosteric galactokinase 1 inhibitors for the treatment of classic galactosaemia
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15.30 - 15.50
Filippo Prischi (University of Essex)
Targeting RSK4 prevents both chemoresistance and metastasis in lung and bladder cancer
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15:50 – 16:35 Coffee Break and Exhibition Viewing
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16:35 – 18.05
PCG: Entropy & Structure
Lecture Theatre RSLT07
Chair: Anthony Phillips  
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in recent years, entropy has become an explicit target of materials design and synthesis: configurational and magnetic entropy can stabilise materials' structures or form the basis of their functionality. Understanding such disorder requires a variety of experimental and computational techniques drawn from the conventional crystallographic arsenal and beyond. In this session we welcome talks on all aspects of order and disorder: quantifying, designing, and exploiting entropy for materials ranging from high-entropy alloys to calorics.
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16.35 - 17.05
Keynote: Xavier Moya (University of Cambridge)
Giant caloric effects near structural phase transitions
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17.05 - 17.25
Guanqun Cai (Queen Mary University of London)
Neutron scattering studies of orientational disorder with the Reverse Monte Carlo method
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17.25 - 17.45
Jonathan Skelton (University of Manchester)
Chemical origin of polymorphism in molecular crystals: first-principles modelling and quantum-chemical topology
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17.45 – 18.05
Emma Wolpert (University of Oxford)
Magnetic textures in non-magnetic materials
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16:35 – 18.05
CCG: Electron crystallography
Lecture Theatre RSLT06
Chair: Simon Parsons
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Electron diffraction is one of the mostly rapidly developing and exciting areas of crystallography. The publication of a number of recent papers describing its application in chemical crystallography has led to a great deal of comment and anticipation in the chemical community. The technique enables crystal structures to be obtained from samples with dimensions of the order of the few microns, or even 100s of nanometres.  The strength of the interaction between electrons and matter that enables such small crystals to be studied carries with it the problem of multiple scattering, meaning that the kinematical model which has been so successful for X-ray and neutron diffraction no longer applies, and dynamical effects need to be taken into account. This session will give an overview of the most recent advances in the field and progress towards making electron diffraction a more widely used technique in the chemical crystallography community.
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16.35 - 17.05
Keynote: Lukas Palatinus (Institute of Physics of the CAS)
Structure refinement from 3D electron diffraction: where are the limits?
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17.05 - 17.25
Fabio Nudelman (University of Edinburgh)
Solid-state transformation and polymorphism in calcium carbonate crystallisation
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17.25 - 17.45
Andy Stewart (University of Limerick)
Electron Diffraction: where does scattering stop and diffraction begin?
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17.45 – 18.05
Duncan Johnstone (University College London)
Multidimensional electron diffraction of organic solids
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16:35 – 18:05
BSG: Time resolved crystallography
Lecture Theatre RSLT05
Chair: Briony Yorke
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Time-resolved crystallography allows the observation of molecular mechanism in real time, providing unique insight into the dynamics that link structure and function. The use of X-ray free electron lasers has pushed the boundaries of time-resolved crystallography, allowing structural changes to be determined with femtosecond time-resolution. The development of serial crystallographic techniques has also initiated a resurgence in synchrotron time-resolved experiments. This session will focus on the exciting developments being made at free-electron laser and synchrotron sources and the science that has been made possible by these developments. Contributions describing these and other structural time-resolved methods are welcomed.
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16.35 - 17.05
Keynote: Jasper Van Thor (Imperial College London)
Optical control of protein structural dynamics by ultrafast TR-SFX
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17.05 - 17.25
Henrike Müller-Werkmeister (University of Potsdam)
Time-resolved serial crystallography reveals water mediated allostery in the enzyme fluoroacetate dehalogenase
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17.25 - 17.45
Lauren Hatcher (University of Cardiff)
LED solutions for time-resolved diffraction on molecular crystal systems
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17.45 - 18.05
Jannik Strauss (University of Leeds)
Asymmetry in membrane-bound pyrophosphatases explored by 
conventional and time-resolved X-ray crystallography 
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18:05 – 18:15 Break
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18.15 - 19.00
PCG Plenary Lecture
Conference Auditorium 2
Chair: Anthony Phillips
Vaclav Petricek (Czech Academy of Sciences)
The role of crystal structure analysis in investigation of crystals with important physical properties
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19:00 – 21:00 
Poster Session with dinner and wine
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Wednesday 8 April, 2020
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08:00 Registration opens for Main Meeting
[Registration open 08:00 – 18:00].
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08.45 - 09.30
IG Plenary Lecture
Conference Auditorium 2
Chair: Angeles Pulido
Marcus Neumann (Avant-garde Materials Simulation)
Detecting and avoiding disappearing polymorph cases by crystal structure prediction
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09:30 – 10:15 Coffee Break and Exhibition Viewing
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10:15 – 11:45
IG/BACG: Crystal growth/pitfalls and challenges in industrial crystallization
Lecture Theatre RSLT06
Chairs: Cheryl Doherty and Linda Seton 
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The control and prediction of crystallisation processes is a challenge but vital in many areas of industry. This session will cover practical and computational methods that aim to link understanding with the development of control strategies and predictive approaches. Talks from the perspectives of crystallisation, solid form and characterisation will be welcome.
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10.15 - 10.45
Keynote: TBC
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10.45 - 11.05
Michael Probert (Newcastle University)
The ENaCt Protocol – changing the face of small molecule crystallisation
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11.05 - 11.25
Harry Geddes (University of Oxford)
Structural characterisation of amorphous solid dispersions via Metropolis matrix factorisation of pair distribution function data
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11.25 - 11.45
Alexandru Moldovan (University of Leeds/Cambridge Crystallographic Data Centre)
Probing the Interface Between Organic Crystals
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PCG: <3D: Structure and Properties of Low-Dimensional Materials
Lecture Theatre RSLT07

Chair: Lucy Clark
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There are many examples of crystalline solids whose structures feature quasi-one-dimensional chains or two-dimensional planes of atoms giving rise to low-dimensional interactions. This results in a diverse array of intriguing physical phenomena, from high-temperature superconductivity in, for example, layered iron arsenides to pronounced magnetocaloric effects in one-dimensional framework solids. Furthermore, since the isolation of graphene, there are has been an explosion of activity in the discovery and characterisation of different classes of two-dimensional crystals with remarkable properties that may underpin future advanced technologies. As such, this session is dedicated to showcasing recent developments of crystallography and complementary characterisation methods in the determination of the fascinating structure-property relationships in a variety of low-dimensional solids.
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10.15 - 10.45
Keynote: Maria Grazia Francesconi (University of Hull)
One –dimensional oxides and non-oxide materials
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10.45 - 11.05
Simon Cassidy (University of Oxford)
Playing with layered structures and interpreting their diffraction
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11.05 - 11.25
Nathan Giles-Donovan (University of Glasgow)
Decoupling of the magnetic order parameter and density waves in Cu3Nb2O8
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11.25 - 11.45
Aly Abdeldaim (University of Liverpool/Rutherford Appleton Laboratory)
Magnetic Orders and Spin Dynamics in Low Dimensional Magnets
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10:15 – 11:45
BSG: Enzymes
Lecture Theatre RSLT05
Chair: Wyatt Yue
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Metabolic enzymes catalyse the biochemical reactions associated with survival and homeostasis in living organisms while the processes governing the behaviour of cells are mediated by tightly regulated cascades and complexes of cell signalling enzymes. Enzymes that perform various types of chemistry are therefore studied intensively in the fields of biochemistry and molecular cell biology. The essentiality of metabolic enzymes is underscored by various genetic and common disorders associated with their deficiency. Enzymes are also central to the field of biotechnology, where they are engineered to manufacture novel products or act upon novel substrates. This session will include examples of work in which structural biology methods are answering important questions relating to the activity and regulation of enzymes, with a view to understanding their functional, biotechnological and therapeutic applications.
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10.15 - 10.45
Keynote: Peter Moody (University of Leicester)
Using neutron crystallography to watch hydrogens in heme enzymes  
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10.45 - 11.05
Stephen Marshall (University of Manchester)
Providing detailed insights into the UbiD-UbiX decarboxylase system
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11.05 - 11.25
Yuliana Yosaatmadja (University of Oxford)
The structure of DNA repair endonuclease, Artemis
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11.25 - 11.45
Henry Bailey (University of Oxford)
Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release
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11.45 – 12:15 Lunch Break and Exhibition Viewing
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12:15 – 12:45
Lecture Theatre RSLT05
BSG Annual General Meeting

12:45 – 13:15
Lecture Theatre RSLT06
CCG Annual General Meeting
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13:15 – 14:45
Conference Auditorium 2
Early Career Prize Lectures
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BSG: Briony Yorke (University of Leeds)
CCG: TBC
PCG: Winner to be announced at the meeting!
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14:45 – 15:30 Coffee Break and Exhibition Viewing
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15:30 – 17:00
IG/CCG: Control & prediction of crystals
Lecture Theatre RSLT06
Chairs: Angeles Pulido and Stuart Kennedy
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This session aims to cover a wide range of research used to control and predict crystals including both experimental and computational tools. We welcome talks on the control and prediction of solid forms, particle and mechanical properties by researchers from a wide range of fields of computational chemistry, informatics, solid state/crystallisation and materials science.
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15.30 - 16.00
Keynote: TBC
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16.00 - 16.20
Andrew Maloney (Cambridge Crystallographic Data Centre)
“Particle Informatics”: Advancing our understanding of particle properties through digital design
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16.20 - 16.40
Andre Frade (University of Oxford)
Increasing the trustworthiness and practical value of machine learning models: a case study predicting hydrogen bond network dimensionalities from molecular diagrams
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16.40 - 17.00
Hari Muddana (OpenEye Scientific Software)
Ab initio prediction of small-molecule crystal structures on the cloud
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15:30 – 17.00
PCG: >3D Structure and Properties of Higher-Dimensional Materials
Lecture Theatre RSLT07
Chair: Phil Lightfoot
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This session targets crystals and materials that go beyond a conventional description using three dimensional axes and indices. This includes aperiodic crystals, quasicrystals and incommensurately modulated crystals, structures, magnetic structures etc. Examples may include compounds exhibiting compositional, structural or spin disorder at the 3D level, but which is amenable to better description and rationalisation using 4D or higher dimensionality. We are interested in examples where the dimensionality may significantly affect materials’ properties, as well as in the fundamental description and understanding of the higher-dimensional crystallography.
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15.30 - 16.00
Keynote: Fabio Orlandi (Rutherford Appleton Laboratory)
Superspace formalism and materials properties
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16.00 - 16.20
Kristen Christensen (University of Oxford)
What the Chemists tries to ignore in their data
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16.20 - 16.40
Chris Howard (University of Newcastle, Australia)
Travels with the Tungsten Bronzes
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16.40 - 17.00
John Claridge (University of Liverpool)
Futher Adventures In Superspace: Where are the atoms, and what does it tell us about properties?
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15.30 – 17.00
BSG: Computational biophysics
Lecture Theatre RSLT05
Chair: Matteo Degiacomi
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To successfully carry out their task in an organism, biomolecules must interact with their designated substrates in a controlled manner. The function of a biomolecule thus emerges from its specific atomic structure and associated dynamics.  Many computational techniques, as diverse as molecular dynamics simulations, homology modelling and protein-protein/ligand docking, can leverage crystallographic data to characterize molecular structure, dynamics and interactions. This session will focus on the application and development of such techniques.
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15:30 – 16.00
Keynote: Franca Fraternali (Kings College London)
Mutations and Variations in Health and Disease:  Protein Interaction Networks and their Multiscale Interpretation
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16.00 - 16.20
Deborah Harrus (EMBL-EBI)
Protein Data Bank in Europe - Knowledge Base (PDBe-KB) – Aggregated views of structural data and functional annotations
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16.20 - 16.40
Matt Batchelor (University of Leeds)
Modelling the structure and dynamic behaviour of phosphorylated Hsp72 nucleotide-binding domains
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16.40 - 17.00
Rod Chalk (Oxford University)
Electrospray Surface Charge Describes Protein Molecular Motion
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17:00 – 17:10 Break
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17.10 - 18.00
Bragg Lecture
Conference Auditorium 2
Chairs: Simon Phillips and Paul Raithby
Richard Henderson (University of Cambridge)
The continuing cryoEM revolution in Structural Biology
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18:00 – 19:00
BCA Annual General Meeting
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19:30 for 20:00
Conference Dinner followed by Ceilidh
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Thursday 9 April 2020
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08:00 Registration opens for Main Meeting
[Registration open 08:00 – 12:00]
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08.45 - 09.30
CCG Plenary Lecture
Conference Auditorium 2
Chair: Hamish Yeung
F Emmerling (Federal Insitute for Materials Reseach and Testing/Humboldt University)
Shaken not stirred: enhancing the flavor of mechanochemistry
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09.30 – 10.15 Coffee Break and Exhibition Viewing
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10.15 – 11.45
CCG: Chemistry in extreme conditions
Lecture Theatre RSLT06
Chair: Hamish Yeung
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Crystallography has traditionally been a major technique with which to understand the structures and reactivity of molecules. This session focuses on how crystallography and other methods can reveal insight into phenomena that occur away from ambient conditions, such as very high or low temperatures, high pressure or electric fields. Think bonding, mechanics, distortions, phase transformations, changes in physical properties etc.––in and ex situ studies allowed!
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10.15 - 10.45
Keynote: Colin Pulham (University of Edinburgh)
Putting the Squeeze on Molecular Materials
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10.45 - 11.05
Lucy Saunders (Diamond Light Source)
In situ single crystal X-ray diffraction studies under an applied electric field on I19, Diamond Light Source
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11.05 - 11.25
Giulia Novelli (University of Edinburgh)
Carbon Molecules in Space: a Thermal Equation of State Study of Solid Hexamethylenetetramine \
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11.25 - 11.45
Christine Beavers (Diamond Light Source)
The future of extreme conditions diffraction at Diamond Light Source  
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10.15 – 11.45
CCG/PCG: Structure solution from powders
Lecture Theatre RSLT07
Chairs: Karen Johnstone and Jeremy Cockcroft
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This joint session between the CCG and PCG explores structure solution from powders in a variety of organic, inorganic and mixed organic/inorganic systems. Despite considerable advances in the field, structure solution from powder diffraction is by no means routine and, increasingly, complementary methods are being used to aid structure determination. We are interested in recent examples where structure solution has been aided by complementary methods, including in situ and in operando techniques as well as total scattering methods. Examples where the combination of experimental and computational methods has resulted in successful structure solution are also of significant interest.
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10.15 - 10.45
Keynote: Kenneth Shankland (University of Reading)
Accelerating and enhancing the effectiveness of crystal structure determination from powder diffraction data
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10.45 - 11.05
Anthony Bell (Sheffield Hallam University)
High temperature phase transitions in synthetic leucite analogues
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11:05 – 11:25
Rachael Smith (University College London)
Quantifying and controlling stacking disorder in silver iodide and other related materials
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11.25 – 11.45
TBC
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10.15 – 11.45
BSG: Membrane proteins
Lecture Theatre RSLT05
Chair: Bonnie Wallace
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Membrane proteins span a wide range of structural and functional types, ranging from multimeric complexes to monomeric or multimeric channels, receptors, and enzymes. They perform very important functions in cells and many are of interest for pharmaceutical development. However, they have proved to be challenging for structural studies due to their amphipathic nature, with both hydrophobic and hydrophilic domains, and the requirement for detergents, amphipols, nanodiscs, and other amphiphiles to solubilise, purify, and stabilise them.  This session will include examples of work demonstrating how recent developments in sample preparation and in the complementary techniques of cryo-Electron Microscopy and X-ray crystallography are enabling structural studies of key membrane proteins.
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10.15 - 10.45
Keynote: Amandine Marechal (University College London/Birkbeck)
Respiratory supercomplexes: what can we learn from yeast?
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10.45 - 11.05
Altin Sula (University of London)
Drug Interactions with the Voltage-Gated Sodium Channel NavMs
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11.05 - 11.25
Steven Harborne (University of Leeds/BioHub)
Improving membrane proteins: combining bioinformatic techniques for selecting stabilising mutations
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11.25 - 11.45
Josh White (University of Leeds)
Investigating the mechanism of SusCD-like TonB-dependent tranporters using cryo-electron microscopy 
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11:45 – 12:00 Coffee Break and Exhibition Viewing
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12.00 – 13.30
PCG: Phase transitions
Lecture Theatre RSLT07
Chair: Lewis Owen
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Phase transitions are of critical importance to our understanding of a materials structure and its physical and chemical properties. This session will aim to explore a broad range of structural phase transitions; from crystalline solid state transformations to crystalline-amorphous transitions. Particular interest will be placed on novel characterisation including  novel experimental set-ups and techniques (e.g. Bragg diffraction, PDF, NMR etc), data-processing methodologies, and structural parameterisation.
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12.00 - 12.30
Keynote: Joesph Hriljac (Diamond Light Source)
Phase transitions in zeolites driven by pressure and ion exchange
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12.30 - 12.50
Paz Vaqueiro (University of Reading)
Jahn-Teller driven metal-to-semiconductor transition in tetrahedrite
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12.50 - 13.10
Jeremy Karl Cockcroft (UCL)
Influence of Solvent in Crystal Engineering: A Significant Change to the Order-Disorder Phase Transition in Ferrocene
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13.10 - 13.30
Paul O'Meara (Malvern Panalytical)
In-situ XRD and PDF investigation of MF3.3H2O (M = Fe, Cr) in controlled atmosphere: accessing new phases with controlled chemistry
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12.00 – 13.30
CCG: Hot & Cold Structures
Lecture Theatre RSLT06
Chairs: Charlie McMonagle
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In this session we look at how temperature can affect materials in a huge number of interesting and useful ways. This could be structural effects, multiple phase behaviour, electronic, and/or magnetic transitions across the entire temperature range. Temperature can be key to phenomena such as superconductivity, phase transitions, spin-crossover, negative thermal expansion, and many others.  Insights into new instrumentation or techniques for accessing these temperatures will also be considered along with combining variable temperature with other stimuli (pressure, light etc.). This session aims to highlight the important role of temperature across a wide range crystallography.
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12.00 - 12.30
Keynote: Sven Lidin (Lund University)
Incommensurate intermetallics - The simple, The challenging and The confusing: Making sense of complexities in reciprocal space
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12:30 – 12.50
X Liu (University of Edinburgh)
Influence of Crystal Packing on the Mechanism of Decomposition of the Acetonitrile-Solvated Cocrystal of Piroxicam and Succinic Acid
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12.50 - 13.10
Jake Musselle-Sexton (Newcastle University)
Synthetic routes to Spin Crossover Complexes
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13.10 – 13.30
Josie Auckett (Durham University)
High-temperature disorder in the oxide-ion conductor Ba3NbWO8.5
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12.00 – 13.30
BSG: Protein-protein interactions
Lecture Theatre RSLT05
Chair: Richard Bayliss
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Cellular processes depend entirely upon interactions between proteins, either for the transient or regulated recognition of one molecule by another in interaction networks or the stable assembly of individual proteins into higher order complexes. Specific molecular recognition in protein-protein interaction networks is crucial in cell signalling while protein complexes function in cells as molecular scaffolds, hubs for cell signalling or as molecular machines carrying out concerted functions. This session will include examples of work in which structural biology methods have been used to determine the molecular basis of interaction between proteins and their assembly into multiprotein complexes.
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12.00 - 12.30
Keynote: Elton Zeqiraj (University of Leeds)
Structure and function of ubiquitin signalling complexes
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12.30 - 12.50
Natalie Tatum (Newcastle University Centre for Cancer)
Biophysical and biological profiling of cancer-associated IRF4 mutants mapped to the novel apo crystal structure confer diverse DNA-binding and transcriptional effects
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12.50 - 13.10
Benazir Alam (Saha Institute of Nuclear Physics)
SerpinB3-mediated regulation of proteolytic activity of lysosomal cysteine proteases
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13.10 - 13.30
Martin Rennie (University of Glasgow)
Ubiquitination of FANCI and FANCD2 stabilize their complex on DNA for interstrand crosslink repair
 
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13:30
Close of BCA Spring Meeting 2020